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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
14.85
Human Site:
S500
Identified Species:
27.22
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
S500
A
G
L
H
R
P
R
S
S
F
D
S
T
T
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
R496
S
N
Y
R
S
C
Q
R
S
D
S
D
A
E
A
Dog
Lupus familis
XP_546691
722
81319
S670
A
G
L
H
R
P
R
S
S
F
D
S
V
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
S500
A
G
L
H
R
A
R
S
S
F
D
S
S
T
A
Rat
Rattus norvegicus
Q09137
552
62239
S500
A
G
L
H
R
P
R
S
S
V
D
S
S
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
K465
S
N
Y
R
S
G
Q
K
N
D
S
D
A
E
A
Chicken
Gallus gallus
Q9IA88
798
88848
F715
E
N
S
F
E
L
A
F
G
G
N
S
Q
L
L
Frog
Xenopus laevis
NP_001088426
560
64038
N506
S
N
N
R
P
P
K
N
E
S
D
P
E
F
Q
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S838
S
L
S
R
F
H
T
S
A
Y
E
Q
L
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
Q463
K
M
S
L
Q
L
Y
Q
V
D
Y
K
S
Y
L
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
R564
P
Q
K
P
A
G
I
R
G
T
R
T
S
S
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
N483
D
E
S
S
I
I
E
N
E
A
A
V
K
S
P
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Q571
D
L
M
K
M
V
I
Q
L
F
Q
I
E
T
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
86.6
86.6
N.A.
6.6
6.6
13.3
20
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
93.3
93.3
N.A.
26.6
13.3
33.3
46.6
N.A.
N.A.
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
0
0
0
8
8
8
0
8
8
8
0
16
0
54
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
0
0
0
0
0
24
39
16
0
0
0
% D
% Glu:
8
8
0
0
8
0
8
0
16
0
8
0
16
16
0
% E
% Phe:
0
0
0
8
8
0
0
8
0
31
0
0
0
8
0
% F
% Gly:
0
31
0
0
0
16
0
0
16
8
0
0
0
0
0
% G
% His:
0
0
0
31
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
16
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
8
8
0
0
8
8
0
0
0
8
8
0
0
% K
% Leu:
0
16
31
8
0
16
0
0
8
0
0
0
8
8
16
% L
% Met:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
31
8
0
0
0
0
16
8
0
8
0
0
0
8
% N
% Pro:
8
0
0
8
8
31
0
0
0
0
0
8
0
0
8
% P
% Gln:
0
8
0
0
8
0
16
16
0
0
8
8
8
0
8
% Q
% Arg:
0
0
0
31
31
0
31
16
0
0
8
0
0
0
0
% R
% Ser:
31
0
31
8
16
0
0
39
39
8
16
39
31
16
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
8
0
8
8
47
0
% T
% Val:
0
0
0
0
0
8
0
0
8
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
8
0
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _